The procoagulant pattern of patients with COVID‐19 acute respiratory distress syndrome

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Procoagulant alveolar microparticles in the lungs of patients with acute respiratory distress syndrome.

Coagulation and fibrinolysis abnormalities are observed in acute lung injury (ALI) in both human disease and animal models and may contribute to ongoing inflammation in the lung. Tissue factor (TF), the main initiator of the coagulation cascade, is upregulated in the lungs of patients with ALI/acute respiratory distress syndrome (ARDS) and likely contributes to fibrin deposition in the air spac...

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TRANSLATIONAL PHYSIOLOGY Procoagulant alveolar microparticles in the lungs of patients with acute respiratory distress syndrome

Bastarache JA, Fremont RD, Kropski JA, Bossert FR, Ware LB. Procoagulant alveolar microparticles in the lungs of patients with acute respiratory distress syndrome. Am J Physiol Lung Cell Mol Physiol 297: L1035–L1041, 2009. First published August 21, 2009; doi:10.1152/ajplung.00214.2009.—Coagulation and fibrinolysis abnormalities are observed in acute lung injury (ALI) in both human disease and ...

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ژورنال

عنوان ژورنال: Journal of Thrombosis and Haemostasis

سال: 2020

ISSN: 1538-7933,1538-7836

DOI: 10.1111/jth.14854